Sumatriptan (Imitrex) is a serotonin 5-HT 1 receptor agonist (triptan).

Use Sumatriptan (Imitrex) as directed by your doctor.

Ask your health care provider any questions you may have about how to use Sumatriptan (Imitrex).

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Burning, numbness, or tingling of the skin; dizziness; drowsiness; feeling of heaviness, pressure, or tightness; feeling strange; mild, temporary flushing; muscle aches; nausea; neck stiffness; pain, swelling, or redness at the injection site; sick feeling; throat or sinus discomfort; tight feeling in the head; tingling; tiredness; vomiting; warm/hot sensation; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody diarrhea; chest pain; confusion; fainting; fast or irregular heartbeat; hearing problems; numbness or tingling of an arm or leg; one-sided weakness; pain, tightness, or pressure in the jaw, neck, or chest; seizures; severe headache, dizziness, or vomiting; severe or prolonged flushing; severe stomach pain; shortness of breath; speech changes; very cold or blue fingers or toes; vision changes or loss of vision; wheezing.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider.

Tell your health care provider if you are taking any other medicines, especially any of the following:

Selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), serotonin norepinephrine reuptake inhibitors (eg, duloxetine), orsibutramine because the risk of a serious side effect called serotonin syndrome may be increased. Symptoms of serotonin syndrome may include mental or mood changes, hallucinations, fast heartbeat, fever, loss of coordination, muscle spasms, increased sweating, nausea, vomiting, or diarrhea
Monoamine oxidase inhibitors (MAOIs) (eg, phenelzine) because they may increase the risk of Sumatriptan (Imitrex)'s side effects
Ergot derivatives (eg, dihydroergotamine, methysergide) or other serotonin 5-HT 1 receptor agonists (eg, eletriptan, rizatriptan) because the risk of their side effects may be increased by Sumatriptan (Imitrex)

This may not be a complete list of all interactions that may occur. Ask your health care provider if Sumatriptan (Imitrex) may interact with other medicines that you take.

In case of overdose, call your local poison control center at 1-800-222-1222.

If the victim has collapsed or is not breathing, call local emergency services at 911.

Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have history of liver or kidney problems, seizures (eg epilepsy), or heart problems

if you have shortness of breath, chest pain, or a history of high blood pressure, heart attack, stroke, high cholesterol, diabetes, or smoking

if you are a woman who is past menopause

if you are a man who is older than 40 years of age

if you are very overweight

if a family member has had heart disease

Do not double doses to make up for a missed dose.

The treatment of migraine headaches with or without aura (eg, flashing lights, wavy lines, dark spots).

Sumatriptan (Imitrex) is also used to treat cluster headaches.

Ask your doctor or pharmacist for more information.

Store away from heat and direct light.

Contact your doctor at once if fast or irregular heartbeat; chest, jaw, or neck pain or numbness; numbness of an arm or leg; severe stomach pain, dizziness, or vomiting; fainting; or vision changes occur.

If you have any questions about Sumatriptan (Imitrex), please talk with your doctor, pharmacist, or other health care provider.