Rosuvastatin (Crestor) is an HMG-CoA reductase inhibitor.

Take Rosuvastatin (Crestor) exactly as directed.

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; sore throat

Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; dark urine; joint pain; muscle pain, tenderness, or weakness (with or without fever or fatigue); pale stools; severe or persistent headache; stomach pain; swelling of the hands, ankles, or feet; yellowing of the eyes or skin

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider.

Tell your health care provider if you are taking any other medicines, especially any of the following:

Fibrates (eg, gemfibrozil, clofibrate), immunosuppressants (eg, cyclosporine), lopinavir/ritonavir or niacin because they may increase the risk of muscle or kidney problems
Anticoagulants (eg, warfarin), cimetidine, ketoconazole, macrolide immunosuppressants (eg, tacrolimus), or spironolactone because the risk of their side effects may be increased by Rosuvastatin (Crestor)

This may not be a complete list of all interactions that may occur. Ask your health care provider if Rosuvastatin (Crestor) may interact with other medicines that you take.

If overdose is suspected, contact your local poison control center or emergency room immediately

Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are planning to become pregnant

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have low blood pressure, a serious infection, kidney problems, an underactive thyroid, diabetes, or a history of seizures

if you are dehydrated or have certain muscle problems (eg, pain, weakness); have increased creatine phosphokinase (CPK) blood levels; or have metabolism, hormonal, or electrolyte problems

if you are on dialysis

if you drink alcohol or have a history of liver problems or alcohol abuse

if you have had an organ transplant or have recently had major surgery or a serious injury

Do not double doses to make up for a missed dose.

Lowering high cholesterol and triglycerides in certain patients.

Rosuvastatin (Crestor) also increases high-density lipoprotein cholesterol levels.

Rosuvastatin (Crestor) may also be used to treat other conditions as determined by your doctor.

Store at room temperature, away from
heat or moisture.

Check with your doctor before drinking alcohol while you are taking Rosuvastatin (Crestor)

Follow the diet and exercise program given to you by your health care provider

Tell your doctor or dentist that you take Rosuvastatin (Crestor) before you receive any medical or dental care, emergency care, or surgery

Women who may become pregnant should use effective birth control while taking Rosuvastatin (Crestor)

Use Rosuvastatin (Crestor) with caution

If you have any questions about Rosuvastatin (Crestor), please talk with your doctor, pharmacist, or other health care provider