Spironolactone (Aldactone) is a potassium-sparing diuretic.

Take Spironolactone (Aldactone) exactly as directed.

Side effects, that may go away during treatment :

abdominal cramping
change in sexual ability.
deepening of voice
diarrhea
dry mouth
excessive thirst
headache
irregular or no menstrual periods
nausea
or breast tenderness in women
or enlarged breasts in men
skin rash
slowed heart rate
unusual muscle weakness
unusual tiredness

If you notice any unusual effects, contact your doctor, nurse, or pharmacist.

Tell your health care provider if you are taking any other medicines, especially any of the following:

Corticosteroids (eg, prednisone) or ACTH because low blood electrolyte levels may occur
Barbiturates (eg, phenobarbital) or narcotics (eg, morphine) because dizziness upon standing may occur
Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), angiotensin II receptor antagonists (eg, valsartan), cyclosporine, macrolide immunosuppressives (eg, tacrolimus), other potassium sparing diuretics (eg, amiloride, triamterene), other aldosterone-blockers (eg, eplerenone), or potassium supplements because high blood potassium levels may occur (eg, listlessness, confusion, abnormal skin sensations of the arms and legs, heaviness of limbs, slowed heart rate, irregular heart rhythm, potentially life-threatening slow or irregular heartbeat)
Nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, indomethacin) because they may decrease Aldactone 's effectiveness and increase the risk of kidney problems and high blood potassium
Digoxin, digitoxin, lithium, nondepolarizing muscle relaxants (eg, tubocurarine), or quinidine because the risk of their side effects and toxicity may be increased by Aldactone
Pressor amines (eg, norepinephrine) because their effectiveness may be decreased by Spironolactone (Aldactone)

This may not be a complete list of all interactions that may occur. Ask your health care provider if Spironolactone (Aldactone) may interact with other medicines that you take.

If overdose is suspected, contact your local poison control center or emergency room immediately.

Spironolactone (Aldactone) has been shown to cause tumors in laboratory animals. Spironolactone (Aldactone) should only be used for the conditions in which it is indicated. Avoid unnecessary use of Spironolactone (Aldactone).

Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have high acidity in your body fluids; low sodium levels in your blood; liver, heart, or lung disease; diabetes; or high urea or nitrogen in your blood

if you have menstrual disease

Do not take a double dose to make up for a missed one.

Treating swelling and fluid retention in patients with congestive heart failure, cirrhosis, or kidney problems.

Spironolactone (Aldactone) is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Store at room temperature below 30 degrees C / 86 degrees F.

Check with your doctor before you use a salt substitute or a product that has potassium in it.

If you have any questions about Spironolactone (Aldactone), please talk with your doctor, pharmacist, or other health care provider.