Ondansetron (Zofran) is an antiemetic.

Ondansetron (Zofran) comes as a tablet and in an injectable form.

The tablets may be taken with or without food.

The first dose of Ondansetron (Zofran) usually is taken in a hospital or clinic 30 minutes before chemotherapy is begun. The second dose is taken 4 hours after the first dose, and the third dose is taken 8 hours after the first dose.

Your doctor also may want you take one tablet every 8 hours for 1 or 2 days after chemotherapy.

Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.

Take Ondansetron (Zofran) exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Ondansetron (Zofran) injections are given by qualified health care professionals.

Although side effects from Ondansetron (Zofran) are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away:

chest pain
constipation
diarrhea
difficulty breathing
drowsiness
dry mouth
headache
lightheadedness
rash

Tell your doctor and pharmacist what prescription and nonprescription medications you are taking, including vitamins.

Tell your doctor and pharmacist if you are allergic to Ondansetron (Zofran), dolasetron (Anzemet), granisetron (Kytril), or any other drugs.

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed.

KEEP THIS MEDICINE out of the reach of children.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Ondansetron (Zofran) is used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, anesthesia, and surgery.

Ondansetron (Zofran) medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Keep this medication in the container it came in, tightly closed, and out of reach of children.

Store it at room temperature and away from excess heat and moisture.

Before taking Ondansetron (Zofran) :

tell your doctor if you have or have ever had liver disease.

tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding.

If you become pregnant while taking Ondansetron (Zofran), call your doctor.